Calcium-Deficient Hydroxyapatite (CDHA), is a non-stoichiometric hydroxyapatite [Ca10-x(HPO4)x(PO4)6-x(OH)2-x; 0<x<1]. It is a bioactive crystalline calcium phosphate mimicking chemically and structurally to the mineral phase of natural bone. CDHA exhibits a reduced calcium to phosphorus atomic ratio (1.50<Ca/P<1.67). This characteristic gives it a resorbable nature resulting in superior physiological solubility and osteoconductivity. Due to its high specific surface area and biomimetic resorption rates, CDHA serves as a critical scaffold for bone tissue engineering, controlled drug delivery systems, and dental regenerative therapies. It is a milky white powder, manufactured under controlled environment.
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